Cell Biology
Programmed cell death is conserved phenomenon from lower eukaryotes to human. Basic well orchestrated program of cell death, also known as apoptosis, plays important role from development to adult organisms to maintain normal cellular homeostasis. This is especially critical in mammals that integrate multiple physiological as well as pathological death signals. The process of apoptosis is initiated in response to infectious agents, different type of stresses ranging from envorimental to cellular stress. Any gain- and loss-of-function of the core apoptotic pathway can be a primary pathogenic event that results in disease. Read More
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